Aspergillus Galactomannan Antigen by EIA, Serum
Orderable EAP code:
Billable EAP Codes:
CPT Codes:
Lab Section:
Turnaround Time:
Routine: 3 to 5 days
Test Schedule:
Monday, Wednesday, and Friday.
Critical Values:
Positive
Specimen Requirements:
4 mL blood collected in a serum separator tube (gold SST) or serum tube (red); Send 2 aliquots of 1mL each frozen serum.
Minimum volume = 2 aliquots of 0.4 mL serum
Collect blood samples according to standard laboratory procedures. Serum samples must be uncontaminated with fungal spores and/or bacteria. Transport and store samples in sealed tubes, unexposed to air.
Unopened samples can be stored at 2-8ºC for up to 5 days prior to testing. After initial opening, serum samples may be stored at 2-8°C for 48 hours prior to testing. For longer storage, store the serum at -70ºC
Pediatric Specimen Requirements:
2 mL blood collected in a serum separator tube (gold SST) or serum tube (red);
Minimum volume = 2 aliquots of 0.4 mL serum.
Collect blood samples according to standard laboratory procedures. Serum samples must be uncontaminated with fungal spores and/or bacteria. Transport and store samples in sealed tubes, unexposed to air.
Unopened samples can be stored at 2-8ºC for up to 5 days prior to testing. After initial opening, serum samples may be stored at 2-8°C for 48 hours prior to testing. For longer storage, store the serum at -70ºC
Reference Range:
Comments:
This test has not been evaluated in neonates and reference ranges have not been established for this age group.
Negative results do not exclude the diagnosis of invasive Aspergillosis.
False negative results may be seen in patients receiving concomitant anti-fungals, and patients with chronic granulomatous disease and Jobs syndrome.
A single positive test result (index equal to or greater than 0.5) should be clinically correlated by testing a separate serum because many agents (e.g. food, antibiotics) may cross-react with the assay. False positive results may also be seen in very young children, patients with altered intestinal barrier, and patients infected with other genre of fungi such as Penicillium, Alternaria, Histoplasma, and Geotrichum.
If invasive Aspergillosis is suspected in high-risk patients, serial sampling is recommended.
Synonyms:
Aspergillus Galactomannan Antigen